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Dojolvi

Generic name: triheptanoin

What is Dojolvi?

Dojolvi is a prescription medicine used to treat long-chain fatty acid oxidation disorders (LC-FAOD) in children and adults.

What should I tell my healthcare provider before taking Dojolvi?

Before taking Dojolvi, tell your healthcare provider about all of your medical conditions, including if you:

  • are pregnant or plan to become pregnant. It is not known if Dojolvi will harm your unborn baby.
    Pregnancy Safety Study. There is a pregnancy safety study for women who take Dojolvi during pregnancy. The purpose of this study is to collect information about your health and your baby’s health. You can talk to your healthcare provider or contact 1-888-756-8657 to enroll in this study or get more information.
  • are breastfeeding or plan to breastfeed. It is not known if Dojolvi passes into breast milk. Talk to your healthcare provider about the best way to feed your baby if you take Dojolvi.
  • are taking a pancreatic lipase inhibitor, such as orlistat, as it may affect how well Dojolvi works.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

How should I take Dojolvi?

  • See the detailed instructions for use that come with Dojolvi for instructions about how to mix and take Dojolvi by mouth in soft foods or drinks or how to mix and give Dojolvi through feeding tubes.
  • Take Dojolvi exactly as your healthcare provider tells you.
  • Your healthcare provider may start you on a low dose of Dojolvi and slowly increase your dose to help avoid side effects. If you are taking another medium chain triglyceride (MCT) product, stop taking the MCT before starting Dojolvi.
  • Do not mix or give Dojolvi using containers, dosing syringes or measuring cups made of polystyrene (a type of plastic that can be solid or foam) or polyvinyl chloride (PVC), a. solid plastic material.
  • Dojolvi should be taken at least 4 times a day with meals or snacks, and always mixed well with soft food or drink.

What are the possible side effects of Dojolvi?

  • Feeding tube problems. Feeding tubes may not work as well or stop working over time when taking Dojolvi. Do not use Dojolvi in feeding tubes made of polyvinyl chloride (PVC). Monitor the feeding tube to make sure it is working properly.
  • Intestinal absorption problems in patients with pancreatic insufficiency. If you have pancreatic insufficiency, consult with your healthcare provider as it may affect how well Dojolvi works.
  • The most common side effects of Dojolvi include:
    • stomach (abdominal) pain
    • diarrhea
    • vomiting
    • nausea

These are not all the possible side effects of Dojolvi. Call your healthcare provider for medical advice about side effects. You may report side effects to Ultragenyx at 1-888-756-8657 or FDA at 1-800-FDA-1088.

General information about the safe and effective use of Dojolvi

Medicines are sometimes prescribed for purposes other than those listed in a Patient Information Leaflet. Do not use Dojolvi for a condition for which it was not prescribed. Do not give Dojolvi to other people, even if they have the same symptoms that you have. It may harm them. You can ask your pharmacist or healthcare provider for information about Dojolvi that is written for health professionals.

How should I store Dojolvi?

  • Store Dojolvi at room temperature between 68°F to 77°F (20°C - 25°C).
  • Do not freeze Dojolvi.
  • When the bottle of Dojolvi has been opened, use within 90 days or by the expiration date on the bottle, whichever comes first.
  • Do not store Dojolvi in containers made of polystyrene or polyvinyl chloride (PVC).

What are the ingredients in Dojolvi?

Dojolvi is made of 100% triheptanoin and contains no other ingredients.

For more information, go to www.dojolvi.com or call 1-888-756-8657.

Source: National Library of Medicine. Last updated June 30, 2020.