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Generic name: ferumoxytol

What is Feraheme?

Feraheme is a prescription medicine used to treat iron deficiency anemia in adults who have:

  • intolerance to oral iron or who have not responded well to treatment with oral iron or
  • chronic kidney disease (CKD)

It is not known if Feraheme is safe and effective in children less than 18 years of age.

What is the most important information I should know about Feraheme?

Feraheme may cause serious side effects including:

  • Serious allergic reactions that can lead to death. Serious allergic reactions have happened in people after receiving the first dose of Feraheme or after receiving additional doses in people who did not previously have an allergic reaction. If you have a history of allergies to many different medicines, you may have an increased risk of serious allergic reactions to Feraheme. Tell your healthcare provider or get medical help right away if you get any of these signs or symptoms:
    • rash
    • itching
    • dizziness or lightheadedness
    • swelling of the tongue or throat
    • wheezing or trouble breathing

See “What are the possible side effects of Feraheme?” for more information about side effects.

Who should not use Feraheme?

Do not receive Feraheme if you:

  • are allergic to Feraheme or any of the ingredients in Feraheme. See the end of this guide for a complete list of ingredients in Feraheme.
  • have had an allergic reaction to any iron medicine given into your vein by intravenous (IV) infusion.

What should I tell my healthcare provider before using Feraheme?

Before receiving Feraheme, tell your healthcare provider about all of your medical conditions, including if you:

  • have allergies to many different medicines
  • have iron overload
  • have low blood pressure (hypotension).
  • are pregnant or plan to become pregnant. It is not known if Feraheme will harm your unborn baby.
  • are breastfeeding or plan to breastfeed. It is not known if Feraheme passes into your breast milk. You and your healthcare provider should decide if you will receive Feraheme or breastfeed.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

How should I use Feraheme?

  • Feraheme will be given to you into your vein by intravenous (IV) infusion over at least 15 minutes by your healthcare provider. You will receive Feraheme in 2 doses 3 to 8 days apart.
  • Your healthcare provider will watch you during and for at least 30 minutes after you receive Feraheme.

What are the possible side effects of Feraheme?

Feraheme can cause serious side effects, including:

  • See “What is the most important information I should know about Feraheme?"
  • Low blood pressure (hypotension) is a common side effect of Feraheme and can sometimes be serious. Your healthcare provider will check you for signs and symptoms of hypotension after each Feraheme infusion.
  • Iron overload. Your healthcare provider will do blood tests to check your iron levels during treatment with Feraheme.

The most common side effects of Feraheme include: diarrhea, headache, nausea, dizziness, constipation, and swelling of your legs, feet, arms, or hands.

These are not all of the possible side effects of Feraheme. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

General information about the safe and effective use of Feraheme

Medicines are sometimes prescribed for purposes other than those listed in a Patient Information leaflet. If you would like more information, talk to your healthcare provider. You can ask your pharmacist or healthcare provider for information about Feraheme that is written for health professionals.

How should I store Feraheme?

Store at 20° to 25°C (68° to 77°F). Excursions permitted to 15° – 30°C (59° – 86°F).

What are the ingredients in Feraheme?

Active ingredient: ferumoxytol

Inactive ingredient: mannitol

For more information, go to or call 1--877-411-2510.

Source: National Library of Medicine. Last updated February 2, 2018.