Dosage Forms
Excipient information presented when available (limited, particularly for generics); consult specific product labeling.
Capsule, Oral:
Panto-250: 250 mg
Tablet, Oral:
Generic: 100 mg, 200 mg, 500 mg
Tablet, Oral [preservative free]:
Generic: 500 mg
Pharmacology
Mechanism of Action
Pantothenic acid is required for the synthesis and maintenance of coenzyme A.
Pharmacokinetics/Pharmacodynamics
Absorption
Absorbed in the intestine
Metabolism
Hydrolyzed in the intestine to coenzyme A
Excretion
Urine
Use: Labeled Indications
Dietary supplement
Dosage and Administration
Dosing: Adult
OTC labeling: Dietary supplement: One tablet daily
Dosing: Geriatric
Refer to adult dosing.
Dietary Considerations
Dietary adequate intake (AI) (IOM 1998):
1 to 6 months: 1.7 mg/day
7 to 12 months: 1.8 mg/day
1 to 3 years: 2 mg/day
4 to 8 years: 3 mg/day
9 to 13 years: 4 mg/day
≥14 years: 5 mg/day
Pregnancy: 6 mg/day
Lactation: 7 mg/day
Drug Interactions
There are no known significant interactions.
Pregnancy
Pregnancy Considerations
Water soluble vitamins cross the placenta (IOM, 1998).
Patient Education
- Discuss specific use of drug and side effects with patient as it relates to treatment. (HCAHPS: During this hospital stay, were you given any medicine that you had not taken before? Before giving you any new medicine, how often did hospital staff tell you what the medicine was for? How often did hospital staff describe possible side effects in a way you could understand?)
- Have patient report immediately to prescriber severe nausea, severe vomiting, or severe diarrhea (HCAHPS).
- Educate patient about signs of a significant reaction (eg, wheezing; chest tightness; fever; itching; bad cough; blue skin color; seizures; or swelling of face, lips, tongue, or throat). Note: This is not a comprehensive list of all side effects. Patient should consult prescriber for additional questions.
Intended Use and Disclaimer: Should not be printed and given to patients. This information is intended to serve as a concise initial reference for health care professionals to use when discussing medications with a patient. You must ultimately rely on your own discretion, experience, and judgment in diagnosing, treating, and advising patients.
