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Ruzurgi

Generic name: amifampridine

What is Ruzurgi used for?

  • Ruzurgi is used to treat myasthenic syndrome of Eaton-Lambert.

Before taking Ruzurgi, tell your doctor:

  • If you are allergic to Ruzurgi; any part of this medicine; or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had.
  • If you have ever had seizures.

This is not a list of all drugs or health problems that interact with this medicine.

Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take Ruzurgi with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

What are some things I need to know or do while I take Ruzurgi?

  • Tell all of your health care providers that you take Ruzurgi. This includes your doctors, nurses, pharmacists, and dentists.
  • This medicine may cause seizures in some patients. Talk with the doctor.
  • Tell your doctor if you are pregnant, plan on getting pregnant, or are breast-feeding. You will need to talk about the benefits and risks to you and the baby.

How is Ruzurgi best taken?

Use Ruzurgi as ordered by your doctor. Read all information given to you. Follow all instructions closely.

  • Take with or without food.
  • Tablet may be broken in half.
  • Keep taking Ruzurgi as you have been told by your doctor or other health care provider, even if you feel well.
  • A liquid (suspension) can be made if needed. If you are not sure how to prepare the suspension, talk with your pharmacist.
  • If a liquid (suspension) is made, shake well before use.
  • Measure liquid doses carefully. Use the measuring device that comes with Ruzurgi. If there is none, ask the pharmacist for a device to measure Ruzurgi.

What do I do if I miss a dose?

  • Skip the missed dose and go back to your normal time.
  • Do not take 2 doses at the same time or extra doses.

What are the side effects of Ruzurgi that I need to call my doctor about immediately?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Signs of high blood pressure like very bad headache or dizziness, passing out, or change in eyesight.
  • Signs of a urinary tract infection (UTI) like blood in the urine, burning or pain when passing urine, feeling the need to pass urine often or right away, fever, lower stomach pain, or pelvic pain.
  • Seizures.
  • A burning, numbness, or tingling feeling that is not normal.
  • Change in eyesight.
  • Swollen gland.
  • Falls.
  • Shortness of breath.
  • Swelling in the arms or legs.
  • Low mood (depression).
  • Muscle weakness that is new or worse.

What are some other side effects of Ruzurgi?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

  • Signs of a common cold.
  • Flu-like signs.
  • Stomach pain or heartburn.
  • Upset stomach.
  • Diarrhea.
  • Constipation.
  • Headache.
  • Back pain.
  • Muscle spasm.
  • Dizziness.
  • Feeling tired or weak.
  • Pain in arms or legs.
  • Trouble sleeping.

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https://www.fda.gov/medwatch.

If overdose is suspected:

If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

Ruzurgi Images

How do I store and/or throw out Ruzurgi?

  • Store at room temperature.
  • Store in a dry place. Do not store in a bathroom.
  • Throw away any part not used after 3 months.
  • If a liquid (suspension) is made from the tablets, store in a refrigerator. Do not freeze. Throw away any part not used after 24 hours.
  • Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
  • Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.

Consumer information use and disclaimer

  • If your symptoms or health problems do not get better or if they become worse, call your doctor.
  • Do not share your drugs with others and do not take anyone else's drugs.
  • This medicine comes with an extra patient fact sheet called a Medication Guide. Read it with care. Read it again each time Ruzurgi is refilled. If you have any questions about Ruzurgi, please talk with the doctor, pharmacist, or other health care provider.
  • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

This information should not be used to decide whether or not to take Ruzurgi or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Ruzurgi. This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using this medicine.

Source: Wolters Kluwer Health. Last updated August 20, 2020.