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Sucraid

Generic name: sacrosidase

What is Sucraid?

Sucraid is an oral replacement therapy for people who were born with a sucrase deficiency, which is part of congenital sucrase-isomaltase deficiency (CSID). People with this condition cannot digest certain sugars.

It is not known if Sucraid is safe and effective in children under 5 months of age.

Who should not take Sucraid?

Do not take or give your child Sucraid if you or your child:

  • are allergic to yeast, yeast products, glycerin (glycerol), or papain. See below for a complete list of ingredients in Sucraid.
  • have had a positive skin test for sacrosidase.

What should I tell my healthcare provider before taking Sucraid?

Before you take or give your child Sucraid, tell your healthcare provider about all of your medical conditions,
including if you or your child:

  • have diabetes. Sucraid can interact with the food in your diet and may change your blood sugar levels. Your healthcare provider will tell you if your diet or diabetes medicines need to be changed.
  • are pregnant or plan to become pregnant. It is not known if Sucraid will harm your unborn baby.
  • are breastfeeding or plan to breastfeed. You and your healthcare provider should decide if you will take Sucraid
  • while breastfeeding.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

How should I take Sucraid?

  • See the detailed Instructions for Use that come with your medication for instructions about the right way to take or give Sucraid.
  • Sucraid should be taken or given exactly as prescribed by your healthcare provider. Do not change the dose of Sucraid without talking to your healthcare provider.
  • Sucraid comes in a 118 mL multiple-dose bottle or a 2 mL single-use container. Your healthcare provider will decide which type of Sucraid is best for you to use at home.
  • The dose of Sucraid depends on body weight. Your healthcare provider will tell you how much Sucraid you should take or give your child.
    • The dose for a child 33 pounds (15 kg) or less is 1 mL or 28 drops of Sucraid in 2 ounces of water, milk, or infant formula.
    • The dose for a child or adult more than 33 pounds (15 kg) is 2 mL or 56 drops of Sucraid in 4 ounces of water, milk, or infant formula.
  • Sucraid can only be dissolved in cold or room temperature water, milk, or infant formula. Do not put Sucraid in warm or hot liquids.
    • Do not dissolve Sucraid with fruit juice. Do not take or give Sucraid with fruit juice.
    • Do not warm or heat the mixed solution before taking or giving Sucraid.
  • Measure your dose or your child’s dose of Sucraid using the measuring scoop that comes with the Sucraid bottle. Do not use a kitchen teaspoon or other measuring device.
  • Sucraid should be taken or given with each meal or snack. Half of the Sucraid dose should be taken at the beginning of each meal or snack. Take or give the remaining Sucraid dose during the meal or snack.
  • Rinse the measuring scoop with water after each use.
  • Sucraid does not break down some sugars found in foods that have starch, such as wheat, rice, and potatoes. Your healthcare provider may tell you to avoid eating foods with starch.

What are the possible side effects of Sucraid?

Sucraid may cause serious side effects, including:

  • Severe allergic reaction can happen in some people taking Sucraid. Symptoms of a severe allergic reaction include:
    • difficulty breathing
    • swelling of the face, lips, mouth, or tongue
    • wheezing

Your healthcare provider may need to monitor you or your child carefully when first starting treatment with Sucraid. Get medical help right away and tell your healthcare provider as soon as possible if you or your child have any of the symptoms listed above.

Other side effects of Sucraid may include:

  • stomach (abdominal) pain
  • nausea
  • constipation
  • headache
  • dehydration
  • vomiting
  • diarrhea
  • difficulty sleeping
  • nervousness

These are not all of the possible side effects of Sucraid.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

General information about the safe and effective use of Sucraid

Medicines are sometimes prescribed for purposes other than those listed in a Patient Information leaflet. Do not use Sucraid for a condition for which it was not prescribed. Do not give Sucraid to other people, even if they have the same symptoms that you have. It may harm them. You can ask your pharmacist or healthcare provider for information about Sucraid that is written for health professionals.

How do I store Sucraid?

  • Store the Sucraid multiple-dose bottle and 2 mL single-use container in the refrigerator between 36°F to 46°F (2°C to 8°C).
  • The Sucraid single-use container may be stored between 59°F to 77°F (15° to 25°C) for up to 3 days.
  • Protect Sucraid from heat and light.

Keep Sucraid and all medicines out of the reach of children.

What are the ingredients in Sucraid?

Active ingredient: sacrosidase.
Inactive ingredients: Citric acid, glycerol, sodium hydroxide, and water.

For more information, go to www.sucraid.com or call 1-866-469-3773.

Instructions for use for Sucraid

Sucraid (Su-kreid)
(sacrosidase)
oral solution

Instructions for use for Sucraid 2 mL Single-Use Container

Read this Instructions for Use before you start taking or giving Sucraid to a child, and each time you get a refill. There may be new information. This information does not take the place of talking to your healthcare provider about your or your child’s medical condition or treatment.

Sucraid oral solution 2mL vials.image

Important information you need to know before taking or giving Sucraid:

  • The 2 mL single-use container is for a child and adult more than 33 pounds (15 kg).
  • Sucraid is supplied in 2 mL single-use containers in a foil pouch. Each foil pouch holds 5 single-use containers.
    Each container is one 2 mL Sucraid dose.
  • Your healthcare provider will decide the right dose of Sucraid for you or your child. Do not change the dose of Sucraid without talking to your healthcare provider.
  • Sucraid can only be dissolved with cold or room temperature water, milk, or infant formula. Do not put Sucraid in warm or hot liquids. Do not dissolve Sucraid with fruit juice. Do not give or take Sucraid with fruit juice.
  • Do not warm or heat the mixed solution before taking or giving Sucraid.
  • Sucraid should be taken or given with each meal or snack. Half of the Sucraid dose should be taken at the beginning of each meal or snack. Take or give the remaining Sucraid dose during the meal or snack.
  • Do not use the Sucraid single-use container if the seal has been damaged. Contact your pharmacist or healthcare provider if you cannot use the Sucraid single-use container.

Supplies needed to take or give Sucraid:

  • 1 Sucraid 2 mL container
  • 4 ounces of cold or room temperature water, milk, or infant formula (not included)
  • Meal or snack (not included)
  • Spoon to mix (not included)

How to take or give Sucraid:

Step 1: Check the expiration date on the Sucraid foil pouch. Do not use Sucraid if it is past the expiration date.

Remove 1 Sucraid 2 mL container from a foil pouch.

Step 2: Twist the cap to the left to remove it from the container. See Figure 1.

Twist the cap to the left to remove it from the container.image

Step 3: Squeeze all the Sucraid solution in the container into 4 ounces of cold or room temperature water, milk, or infant formula. See Figure 2.

Squeeze all the Sucraid solution in the container into 4 ounces of cold or room temperature water, milk, or infant formula.image

Step 4: Mix your or your child’s prescribed dose in 4 ounces of cold or room temperature water, milk, or infant formula.
See Figure 3.

Mix your or your child’s prescribed dose in 4 ounces of cold or room temperature water, milk, or infant formula.image

Step 5: Take or give half of the mixed solution at the beginning of each meal or snack. Take or give the remaining mixed solution during the meal or snack.

Throwing away (disposal of) Sucraid:

  • Throw away expired or empty Sucraid containers in your household trash.

How should I store Sucraid?

  • Store the Sucraid single-use container in the refrigerator between 36°F to 46°F (2°C to 8°C).
  • The Sucraid single-use container may be stored between 59°F to 77°F (15° to 25°C) for up to 3 days.
  • Protect Sucraid from heat and light.

Keep Sucraid and all medicines out of the reach of children.

Instructions for use issued 05/2022.

Instructions for use for Sucraid 118 mL Multiple-Dose Bottle

Read this Instructions for Use before you start taking or giving Sucraid to a child, and each time you get a refill. There may be new information. This information does not take the place of talking to your healthcare provider about your or your child’s medical condition or treatment.

sucraid 118ml bottle.image

Important information you need to know before taking or giving Sucraid:

  • Your healthcare provider will decide the right dose of Sucraid for you or your child. Do not change the dose of Sucraid without talking to your healthcare provider.
  • The dose of Sucraid depends on body weight. Your healthcare provider will tell you how much Sucraid you should take or give your child.
    • The dose for a child 33 pounds (15 kg) or less is 1 mL or 28 drops of Sucraid in 2 ounces of water, milk, or infant formula.
    • The dose for a child or adult more than 33 pounds (15 kg) is 2 mL or 56 drops of Sucraid in 4 ounces of water, milk, or infant formula.
  • Sucraid can only be dissolved with cold or room temperature water, milk, or infant formula. Do not put Sucraid in warm or hot liquids. Do not dissolve Sucraid with fruit juice. Do not take or give Sucraid with fruit juice.
  • Do not warm or heat the mixed solution before taking or giving Sucraid.
  • Measure your dose or your child’s dose of Sucraid using the measuring scoop that comes with the Sucraid bottle. Do not use a kitchen teaspoon or other measuring device.
  • Sucraid should be taken or given with each meal or snack. Half of the Sucraid dose should be taken or given at the beginning of each meal or snack. Take or give the remaining Sucraid dose during the meal or snack.
  • Do not use the Sucraid multiple-dose bottle if the seal has been damaged. Contact your pharmacist or healthcare provider if you cannot use the Sucraid multiple-dose bottle.

Supplies needed to take or give Sucraid:

  • Sucraid 118 mL multiple-dose bottle
  • 1 measuring scoop (included in Sucraid carton)
  • 2 to 4 ounces of cold or room temperature water, milk, or infant formula (not included)
  • Meal or snack (not included)

How to take or give Sucraid:

Step 1: Check the expiration date on the Sucraid bottle. Do not use Sucraid after the expiration date on the bottle has passed.

Step 2: Write down the date the bottle is first opened in the space provided on the bottle label.

Step 3: Each bottle of Sucraid has a plastic screw cap that covers a dropper dispensing tip. Remove the plastic screw cap by twisting it to the left.

Step 4: Use the measuring scoop that comes in your Sucraid carton to measure your or your child’s prescribed dose. See Figure 1. Reseal the bottle after each use by replacing and twisting the plastic screw cap to the right until tight.

Use the measuring scoop that comes in your Sucraid carton to measure your or your child’s prescribed dose.image

Step 5: Mix your or your child’s prescribed dose in 2 ounces or 4 ounces of cold or room temperature water, milk, or infant formula as instructed by your healthcare provider. See Figure 2.

 Mix your or your child’s prescribed dose in 2 ounces or 4 ounces of cold or room temperature water, milk, or infant formula as instructed by your healthcare provider.image

Step 6: Take or give half of the mixed solution at the beginning of each meal or snack. Take or give the remaining mixed solution during the meal or snack.

Step 7: Rinse the measuring scoop with water after each use.

Throwing away (disposal of) Sucraid:

  • Throw away (discard) the Sucraid multiple-dose bottle and any remaining medicine in your household trash 4 weeks after first opening.

How should I store Sucraid?

  • Store the Sucraid multiple-dose bottle in the refrigerator between 36°F to 46°F (2°C to 8°C).
  • Protect Sucraid from heat and light.

Keep Sucraid and all medicines out of the reach of children.

Instructions for use issued 05/2022.

Source: National Library of Medicine. Last updated May 26, 2022.