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Generic name: tapinarof

What is Vtama?

Vtama cream is a prescription medicine used on the skin (topical) to treat plaque psoriasis in adults.

It is not known if Vtama cream is safe and effective in children with psoriasis under 18 years of age.

What is the most important information I should know about Vtama?

Vtama cream is for use on the skin (topical use) only. Do not use Vtama cream in your eyes, mouth, or vagina.

What should I tell my healthcare provider before using Vtama?

Before using Vtama cream, tell your healthcare provider about all of your medical conditions, including if you:

  • are pregnant or plan to become pregnant. It is not known if Vtama cream will harm your unborn baby.
  • are breastfeeding or plan to breastfeed. It is not known if Vtama cream passes into your breast milk. Talk to your healthcare provider about the best way to feed your baby during treatment with Vtama cream.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements

How should I use Vtama?

  • Use Vtama cream exactly as your healthcare provider tells you to use it.
  • Apply a thin layer of Vtama cream only to your psoriasis skin lesions 1 time a day. Avoid applying Vtama cream to unaffected areas of your skin.
  • Wash your hands after applying Vtama cream unless you are using it to treat your hands.
  • If someone else applies Vtama cream for you, they should wash their hands after application.

What are the possible side effects of Vtama?

The most common side effects of Vtama cream include:

  • red raised bumps around the hair pores (folliculitis)
  • pain or swelling in the nose and throat (nasopharyngitis)
  • skin rash or irritation including itching and redness, peeling, burning, or stinging
  • headache
  • itching
  • flu

These are not all the possible side effects of Vtama cream.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

General information about the safe and effective use of Vtama

Medicines are sometimes prescribed for purposes other than those listed in a Patient Information leaflet. Do not use Vtama cream for a condition for which it was not prescribed. Do not give Vtama cream to other people, even if they have the same symptoms that you have. It may harm them. You can ask your pharmacist or healthcare provider for information about Vtama cream that is written for health professionals.

How should I store Vtama?

  • Store Vtama cream at room temperature between 68°F to 77°F (20°C to 25°C).
  • Do not freeze Vtama cream.
  • Protect Vtama cream from exposure to excessive heat.
  • Keep Vtama cream and all medicines out of the reach of children.

What are the ingredients in Vtama?

Active ingredient: tapinarof

Inactive ingredients: benzoic acid, butylated hydroxytoluene, citric acid monohydrate, diethylene glycol monoethyl ether, edetate disodium, emulsifying wax, medium-chain triglycerides, polyoxyl 2 stearyl ether, polyoxyl 20 stearyl ether, polysorbate 80, propylene glycol, purified water, and sodium citrate dihydrate.

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Source: National Library of Medicine. Last updated May 23, 2022.