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Generic name: permethrin

What is Nix?

Nix is a creme rinse used to treat head lice.

Who should not use Nix?

Do not use:

  • on children under 2 months of age
  • near the eyes
  • inside the nose, ear, mouth, or vagina
  • on lice in eyebrows or eyelashes. See your doctor.

What should I tell my healthcare provider before using Nix?

Tell a doctor before use if you are:

  • allergic to ragweed. May cause breathing difficulty or an asthmatic episode.
  • pregnant or breastfeeding.

How should I use Nix?

When using this product:

  • keep eyes tightly closed and protect eyes with a washcloth or towel,
  • if product gets into the eyes, immediately flush with large amounts of water,
  • scalp itching or redness may occur.
  • Nix is for external use only. If swallowed, get medical help or contact a Poison Control Center right away.

Step 1: Inspect

  • all household members should be checked by another person for lice and/or nits (eggs),
  • use a magnifying glass in bright light to help you see the lice and nits (eggs),
  • use a tool, such as a comb or two unsharpened pencils to lift and part the hair,
  • look for tiny nits near the scalp, beginning at the back of the neck and behind the ears,
  • small sections of hair (1-2 inches wide) should be examined at a time,
  • unlike dandruff, nits stick to the hair. Dandruff should move when lightly touched,
  • if either lice or nits (eggs) are found, treat with Nix Creme Rinse.

Step 2: Treat

  • wash hair with a shampoo without conditioner. Do not use a shampoo that contains a conditioner or a conditioner alone since this may decrease the activity of Nix. Rinse with water.
  • towel dry hair so it is damp but not wet,
  • shake the bottle of Nix well,
  • completely saturate the hair and scalp with Nix. Begin to apply Nix behind the ears and at the back of the neck,
  • keep Nix out of the eyes. Protect the eyes with a washcloth or towel,
  • leave Nix on the hair for 10 minutes, but no longer,
  • rinse with warm water,
  • towel dry hair and comb out tangles,
  • if live lice are seen seven days or more after the first treatment, a second treatment should be given.

Step 3: Remove Lice/Nits

  • remove nits by combing the hair with the special small tooth comb provided. Remaining nits may be removed by hand (using a throw-away glove), or cutting the nits out.
  • use the nit comb provided and make sure the hair remains slightly damp while removing nits,
  • if the hair dries during combing, dampen it slightly with water,
  • part the hair into 4 sections. Work on one section at a time. Longer hair may take more time (1-2 hours),
  • start at the top of the head on the section you have picked,
  • with one hand, lift a 1-2 inch wide strand of hair. Get the teeth of the comb as close to the scalp as possible and comb with a firm, even motion away from the scalp to the end of the hair,
  • use clips to pin back each strand of hair after you have combed out the nits,
  • clean the comb completely as you go. Wipe the nits from the comb with a tissue and throw away the tissue in a sealed plastic bag to prevent the lice from coming back,
  • after combing, recheck the entire head for nits and repeat combing if necessary,
  • check the affected head daily to remove any nits that you might have missed.

What are the possible side effects of Nix?

Stop use and see a doctor if:

  • breathing difficulty occurs
  • eye irritation occurs
  • skin or scalp irritation continues or infection occurs

How should I store Nix?

Store at 20° to 25°C (68° to 77°F).

Store Nix in the carton. The carton contains important information.

Keep out of reach of children.

What are the ingredients in Nix?

Active ingredient: permethrin

Inactive ingredients: balsam canada, cetyl alcohol, citric acid, FD&C yellow no. 6, fragrance, hydrolyzed animal protein, hydroxyethylcellulose, polyoxyethylene 10 cetyl ether, propylene glycol, stearalkonium chloride, water, isopropyl alcohol, methylparaben, and propylparaben.

Source: National Library of Medicine. Last updated April 2, 2018.