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Generic name: ivermectin

What is Sklice?

Sklice Lotion is an over-the-counter (OTC) medicine for topical use on the hair and scalp only. Sklice Lotion is used to treat head lice in people 6 months of age and older.

It is not known if Sklice Lotion is safe and effective for children under 6 months of age.

What is the most important information I should know about Sklice?

For external use only on scalp hair and scalp only. Do not use:

  • On children under 6 months of age
  • Near the eyes
  • Inside the nose, ear, mouth, or vagina
  • On lice in eyebrows or eyelashes. See a healthcare provider if lice are present in these areas.
  • An adult should supervise children aged under 12 using this product.

What should I tell my healthcare provider before using Sklice?

Before you use Sklice Lotion, tell your healthcare provider or pharmacist about all of your medical conditions, including if you or your child:

  • have any skin conditions or sensitivities
  • are pregnant or plan to become pregnant. It is not known if Sklice Lotion can harm your unborn baby
  • are breastfeeding or plan to breastfeed. Ivermectin has been found in breast milk when taken by mouth and may pass into breast milk after using Sklice Lotion. If you use Sklice Lotion and breastfeed your baby:
    • avoid accidental transfer of Sklice Lotion to your breast to help prevent ingestion by your baby.
    • talk to your healthcare provider or pharmacist about the best way to feed your baby during treatment with Sklice Lotion.

How should I use Sklice?

  • See the detailed instructions for use that come with Sklice.
  • Keep eyes tightly closed and protect eyes with a washcloth or towel.
  • If product gets into eyes, gently flush with water.


  • All household members should be checked by another person for lice and/or nits (eggs).
  • Use a magnifying glass in bright light to help you see the lice and/or nits (eggs).
  • Use a tool, such as a comb or two unsharpened pencils to lift and part the hair.
  • Look for tiny nits near the scalp, beginning at the back of the neck and behind the ears.
  • Examine small sections of the hair (1-2 inches wide) at a time.
  • Unlike dandruff, nits stick to the hair. Dandruff should move when lightly touched.
  • If either lice or nits (eggs) are found, treat with product.


  • Your hair and scalp must be dry before applying product.
  • Use the top of cap to break the tamper seal on the tube.
  • Apply product directly to dry hair and scalp.
  • Completely cover your scalp and hair closest to the scalp first, and then apply outwards towards the ends of your hair.
  • Use only amount to completely cover hair and scalp, up to 1 entire tube, and discard the remaining.
  • Rub product throughout your hair
  • It is important to completely cover your entire head so that all lice and eggs are exposed to the lotion. Be sure that each hair is coated from the scalp to the tip.

Wait and rinse

  • Allow product to stay on your hair and scalp for 10 minutes after it has been applied. Use a timer or clock. Start timing after you have completely covered your hair and scalp with product.
  • After 10 minutes, rinse product completely from your hair and scalp using only water.
  • After rinsing, dry and style as usual. Wait 24 hours before applying shampoo.

After treatment

  • Wash your hands after applying product.
  • Nit combing is not necessary when treating with product for it to work, but if desired, a fine-tooth comb or special nit comb may be used to remove dead lice and nits.
  • This is a single use product. Discard tube after use.
  • Do not use again on the same person and same lice infestation without talking to a healthcare provider first.
  • If infestation continues, see a healthcare provider for other treatments.
  • Machine wash any bedding and clothing used by anyone having lice. Machine wash at high temperatures (150°F) and tumble in a hot dryer for 20 minutes.
  • After finishing treatment with lice medicine, check everyone in your family for lice after one week. Consider treatment for those who have lice.

What are the possible side effects of Sklice?

Side effects of Sklice Lotion include:

  • eye redness or soreness
  • eye irritation
  • dandruff
  • dry skin
  • burning sensation of the skin
  • skin or scalp irritation continues or infection occurs
  • rash develops

These are not all the possible side effects of Sklice Lotion. For more information, ask your healthcare provider or pharmacist.

Call your healthcare provider or pharmacist for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

How should I store Sklice?

  • Store Sklice Lotion at room temperature between 68°F to 77°F (20°C to 25°C).
  • Do not freeze Sklice Lotion.
  • Safely throw away any unused Sklice Lotion.
  • Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center (1-800-222-1222) right away.
  • Keep carton and see Consumer Information Leaflet and warnings before use.

For more information contact 1-866-516-4950 Monday – Friday: 9 am – 5 pm EST.

What are the ingredients in Sklice?

Active ingredient: ivermectin

Inactive ingredients: acetylated lanolin alcohol, cetyl acetate, citric acid, cyclomethicone, lanolin alcohol, methylparaben, oleyl alcohol, olive oil, polysorbate 80, propylparaben, shea butter, sodium citrate, sorbitan tristearate, and water.

Source: Food and Drug Administration (FDA). Last updated October 27, 2020.