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Proair HFA

Generic name: albuterol sulfate

What is Proair HFA?

Proair HFA is a prescription medicine used in people 4 years of age and older to:

It is not known if Proair HFA is safe and effective in children under 4 years of age.

Who should not use Proair HFA?

Do not use Proair HFA if you are allergic to albuterol sulfate or any of the ingredients in Proair HFA. See the end of this leaflet for a complete list of ingredients in Proair HFA.

What should I tell my healthcare provider before I use Proair HFA?

Before you use Proair HFA, tell your doctor if you:

  • have heart problems
  • have high blood pressure (hypertension)
  • have convulsions (seizures)
  • have thyroid problems
  • have diabetes
  • have low potassium levels in your blood
  • are pregnant or plan to become pregnant. It is not known if Proair HFA will harm your unborn baby. Talk to your doctor if you are pregnant or plan to become pregnant.
  • are breastfeeding or plan to breastfeed. It is not known if Proair HFA passes into your breast milk. Talk to your doctor about the best way to feed your baby if you are using Proair HFA.

Tell your doctor about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements.

Proair HFA and other medicines may affect each other and cause side effects. Proair HFA may affect the way other medicines work, and other medicines may affect the way Proair HFA works.

Especially tell your doctor if you take:

  • other inhaled medicines or asthma medicines
  • beta blocker medicines
  • diuretics
  • digoxin
  • monoamine oxidase inhibitors
  • tricyclic antidepressants

Ask your doctor or pharmacist for a list of these medicines if you are not sure.

Know the medicines you take. Keep a list of them to show your doctor and pharmacist when you get a new medicine.

How should I use Proair HFA?

  • For detailed instructions, see the instructions for use that comes with Proair HFA.
  • Use Proair HFA exactly as your doctor tells you to use it.
  • If your child needs to use Proair HFA, watch your child closely to make sure your child uses the inhaler correctly. Your doctor will show you how your child should use Proair HFA.
  • Each dose of Proair HFA should last up to 4 hours to 6 hours.
  • Do not increase your dose or take extra doses of Proair HFA without first talking to your doctor.
  • Get medical help right away if Proair HFA no longer helps your symptoms.
  • Get medical help right away if your symptoms get worse or if you need to use your inhaler more often.
  • While you are using Proair HFA, do not use other inhaled rescue medicines and asthma medicines unless your doctor tells you to do so.
  • Call your doctor if your asthma symptoms like wheezing and trouble breathing become worse over a few hours or days. Your doctor may need to give you another medicine (for example, corticosteroids) to treat your symptoms.

What are the possible side effects of Proair HFA?

Proair HFA may cause serious side effects, including:

  • worsening trouble breathing, coughing and wheezing (paradoxical bronchospasm). If this happens stop using Proair HFA and call your doctor or get emergency help right away. Paradoxical bronchospasm is more likely to happen with your first use of a new canister of medicine.
  • heart problems including faster heart rate and higher blood pressure
  • possible death in people with asthma who use too much Proair HFA
  • allergic reactions. Call your doctor right away if you have the following symptoms of an allergic reaction:
    • itchy skin
    • swelling beneath your skin or in your throat
    • rash
    • worsening trouble breathing
  • low potassium levels in your blood
  • worsening of other medical problems in people who also use Proair HFA including increases in blood sugar

The most common side effects of Proair HFA include:

  • your heart feels like it is pounding or racing (palpitations)
  • chest pain
  • fast heart rate
  • shakiness
  • nervousness
  • headache
  • dizziness
  • sore throat
  • runny nose

Tell your doctor if you have any side effect that bothers you or that does not go away.

These are not all of the possible side effects of Proair HFA. For more information, ask your doctor or pharmacist.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Drug Interactions

A total of 400 medications are known to interact with Proair HFA. Use the Interactions Checker Tool.

Common Interactions Checks

General Information about the safe and effective use of Proair HFA

Medicines are sometimes prescribed for purposes other than those listed in a Medication Guide. Do not use Proair HFA for a condition for which it was not prescribed. Do not give Proair HFA to other people, even if they have the same symptoms that you have. It may harm them.

This Patient Information summarizes the most important information about Proair HFA. If you would like more information, talk with your doctor. You can ask your pharmacist or doctor for information about Proair HFA that is written for health professionals.

For more information, go to or call 1-888-482-9522.

How should I store Proair HFA?

  • Store Proair HFA at room temperature between 59° F and 77° F (15° C and 25° C).
  • Avoid exposure to extreme heat and cold.
  • Shake the Proair HFA canister well before use.
  • Do not puncture the Proair HFA canister.
  • Do not store the Proair HFA canister near heat or a flame. Temperatures above 120° F may cause the canister to burst.
  • Do not throw the Proair HFA canister into a fire or an incinerator.
  • Avoid spraying Proair HFA in your eyes.

Keep Proair HFA and all medicines out of the reach of children.

What are the ingredients in Proair HFA?

Active ingredient: albuterol sulfate

Inactive ingredients: propellant HFA-134a and ethanol.

Source: National Library of Medicine. Last updated June 17, 2019.