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Solodyn

Generic name: minocycline hydrochloride

What is Solodyn?

Solodyn is a tetracycline-class drug. Solodyn is prescription medicine used to treat pimples and red bumps (non-nodular inflammatory lesions) that happen with moderate to severe acne vulgaris in people 12 years and older. Solodyn is not effective for acne that is not red-looking (this means acne that is not inflammatory).

It is not known if Solodyn is:

  • safe for use longer than 12 weeks.
  • safe and effective for the treatment of infections.
  • safe and effective in children under the age of 12 years.

Who should not take Solodyn?

Do not take Solodyn if you are allergic to tetracycline-class drugs. Ask your doctor or pharmacist for a list of these medicines if you are not sure.

What should I tell my healthcare provider before taking Solodyn?

Before you take Solodyn, tell your doctor if you:

  • have kidney problems. Your doctor may prescribe a lower dose of medicine for you.
  • have liver problems.
  • have diarrhea or watery stools.
  • have vision problems.
  • plan to have surgery with general anesthesia.
  • have any other medical conditions.
  • are a male, and you and your female partner are trying to conceive a baby. You should not take Solodyn.
  • are pregnant or plan to become pregnant. Solodyn may harm your unborn baby. Taking Solodyn while you are pregnant may cause serious side effects on the growth of bone and teeth of your baby. Talk to your doctor before taking Solodyn if you plan to become pregnant or if you are already taking Solodyn and plan to become pregnant. Stop taking Solodyn and call your doctor right away if you become pregnant while taking Solodyn.
  • are breastfeeding or plan to breastfeed. Solodyn passes into your milk and may harm your baby. You and your doctor should decide if you will take Solodyn or breastfeed. You should not do both.

Tell your doctor about all the other medicines you take including prescription and nonprescription medicines, vitamins, and herbal supplements. Solodyn may affect the way other medicines work, and other medicines may affect how Solodyn works.

Especially tell your doctor if you take:

  • birth control pills. Solodyn may make your birth control pills less effective. You could become pregnant. You should use a second form of birth control while taking Solodyn.
  • a blood thinner medicine.
  • a penicillin antibiotic medicine. Solodyn and penicillins should not be used together.
  • antacids that contain aluminum, calcium, or magnesium or iron-containing products.
  • an acne medicine that contains isotretinoin (Amnesteem, Claravis, Sotret). Solodyn and isotretinoin should not be used together.

Ask your doctor or pharmacist if you are not sure if your medicine is one that is listed above.

Know the medicines you take. Keep a list of them to show your doctor and pharmacist.

How should I take Solodyn?

  • Take Solodyn exactly as your doctor tells you.
  • Skipping doses or not taking all doses of Solodyn may:
    • make the treatment not work as well.
    • increase the chance that the bacteria will become resistant to Solodyn.
  • Solodyn can be taken with or without food. Taking Solodyn with food may lower your chances of getting irritation or ulcers in your esophagus. Your esophagus is the tube that connects your mouth to your stomach.
  • Swallow Solodyn Tablets whole. Do not chew, crush, or split the tablets.

If you take too much Solodyn, call your doctor or poison control center right away. Your doctor may do blood tests to check you for side effects during treatment with Solodyn.

What should I avoid while taking Solodyn?

  • Avoid sunlight, sunlamps, and tanning beds. Solodyn can make your skin sensitive to the sun and the light from sunlamps and tanning beds. You could get severe sunburn.
  • Protect your skin while out in sunlight.
  • You should not drive or operate dangerous machinery until you know how Solodyn affects you. Solodyn may cause you to feel dizzy or light-headed, or have a spinning feeling (vertigo).

What are the possible side effects of Solodyn?

Solodyn may cause serious side effects, including:

  • Harm to an unborn baby. See “What should I tell my doctor before taking Solodyn?"
  • Permanent teeth discoloration. Solodyn may permanently turn a baby’s or child's teeth yellow-grey-brown during tooth development. Solodyn should not be used during tooth development. Tooth development happens in the last half of pregnancy, and from birth to 8 years of age. See “What should I tell my doctor before taking Solodyn?"
  • Intestine infection (pseudomembranous colitis). Pseudomembranous colitis can happen with most antibiotics, including Solodyn. Call your doctor right away if you get watery diarrhea, diarrhea that does not go away, or bloody stools.
  • Serious liver problems. Stop taking Solodyn and call your doctor right away if you get any of the following symptoms of liver problems:
    • loss of appetite
    • tiredness
    • diarrhea
    • yellowing of your skin or the whites of your eyes
    • unexplained bleeding
    • confusion
    • sleepiness
  • Central nervous system effects. See “What should I avoid while taking Solodyn?" Central nervous system effects such as light-headedness, dizziness, and a spinning feeling (vertigo) may go away during your treatment with Solodyn or if treatment is stopped.
  • Benign intracranial hypertension, also called pseudotumor cerebri. This is a condition where there is high pressure in the fluid around the brain. This swelling may lead to vision changes and permanent vision loss. Stop taking Solodyn and tell your doctor right away if you have blurred vision, vision loss, or unusual headaches.
  • Immune system reactions including a lupus-like syndrome, hepatitis, and inflammation of blood or lymph vessels (vasculitis). Using Solodyn for a long time to treat acne may cause immune system reactions. Tell your doctor right away if you get a fever, rash, joint pain, or body weakness. Your doctor may do tests to check your blood for immune system reactions.
  • Serious rash and allergic reactions. Solodyn may cause a serious rash and allergic reactions that may affect parts of your body such as your liver, lungs, kidneys, and heart. Sometimes these can lead to death.
  • Stop taking Solodyn and get medical help right away if you have any of these symptoms:
    • skin rash, hives, sores in your mouth, or your skin blisters and peels
    • swelling of your face, eyes, lips, tongue, or throat
    • trouble swallowing or breathing
    • blood in your urine
    • fever, yellowing of the skin or the whites of your eyes, dark colored urine
    • pain on the right side of the stomach area (abdominal pain)
    • chest pain or abnormal heartbeats
    • swelling in your legs, ankles, and feet
    • darkening of your nails, skin, eyes, scars, teeth, and gums

The most common side effects of Solodyn include:

  • headache
  • tiredness
  • dizziness or spinning feeling
  • itching

Call your doctor if you have a side effect that bothers you or that does not go away. Your doctor may do tests to check you for side effects during treatment with Solodyn.

These are not all the side effects with Solodyn. Ask your doctor or pharmacist for more information.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects to Valeant Pharmaceuticals North America LLC at 1-800-321-4576.

Solodyn Images

General information about the safe and effective use of Solodyn

Medicines are sometimes prescribed for purposes other than those listed in the Patient Information leaflet. Do not use Solodyn for a condition for which it was not prescribed. Do not give Solodyn to other people, even if they have the same symptoms you have. It may harm them.

This Patient Information leaflet summarizes the most important information about Solodyn. If you would like more information, talk to your doctor. You can ask your doctor or pharmacist for information about Solodyn that is written for health professionals.

For more information, call 1-800-321-4576.

How should I store Solodyn?

  • Store Solodyn between 59°F to 86°F (15°C to 30°C).
  • Keep Solodyn Tablets in the container that it comes in and keep the container tightly closed.
  • Keep Solodyn Tablets dry.

Keep Solodyn and all medicines out of the reach of children.

What are the ingredients in Solodyn?

Active ingredient: minocycline HCl.

Inactive ingredients: lactose monohydrate, hypromellose type 2910, magnesium stearate, colloidal silicon dioxide, and carnauba wax.

The 55 mg tablets also contain Opadry II Pink which contains: hypromellose type 2910, titanium dioxide, lactose monohydrate, polyethylene glycol 3350, triacetin, and FD&C Red #40.

The 65 mg tablets also contain Opadry II Blue which contains: hypromellose type 2910, lactose monohydrate, FD&C Blue #1, polyethylene glycol 3350, FD&C Blue #2, titanium dioxide, triacetin, and D&C Yellow #10.

The 80 mg tablets also contain Opadry II Gray which contains: hypromellose type 2910, lactose monohydrate, polyethylene glycol 3350, FD&C Blue #2, FD&C Red #40, titanium dioxide, triacetin, and FD&C Yellow #6.

The 105 mg tablets also contain Opadry II Purple which contains: hypromellose type 2910, lactose monohydrate, titanium dioxide, D&C Red #27, polyethylene glycol 3350, triacetin, and FD&C Blue #1.

The 115 mg tablets also contain Opadry II Green which contains: hypromellose type 2910, lactose monohydrate NF, D&C Yellow #10, triacetin, FD&C Blue #1, titanium dioxide, and FD&C Blue #2.

Source: National Library of Medicine. Last updated September 12, 2017.